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Water: Designed for Life, Part 1 (of 7)

Throughout May and June, we will be presenting an article series from guest writers John Millam, Ken Klos, and Iain D. Sommerville on the amazing properties of water. In part 1, the authors discuss the nature of water’s solvation ability and its importance for sustaining life on Earth.

Water is a simple triatomic molecule, but its behavior is very complex. No chemist, biologist, or physicist would dare to say that water has been thoroughly studied or that how it functions on a molecular scale in either living or nonliving systems is completely understood.1

Water is the substance of life. It makes up about 60 percent of the human body. Without this precious liquid, we would all die. Yet it is so ubiquitous on Earth that we often take it for granted, failing to recognize its significance.

Everything around us, from the tiniest cell to the planet’s climate, is influenced by water. For example:

  • Water serves as the liquid solvent in which life’s biochemical reactions take place.2
  • Water is required for transport of nutrients and waste within plants and animals.
  • Water plays a key role in global temperature regulation.
  • Water is essential for the water cycle (evaporation, condensation, precipitation, runoff, etc.).
  • Water causes erosion of rocks (necessary for the development of soil and the release of vital elements).
  • Water is useful for human transportation, commerce, and recreation (e.g., boating).
  • Water is essential for cooling the bodies of humans and other mammals through perspiration and panting.
  • Water provides a host environment for aquatic life.
  • Water lubricates Earth’s tectonic plates.3

In this series, we intend to explore the question: Why is water so uniquely necessary for our existence?

Water as the Universal Solvent

Water ranks as one of the simplest molecules (consisting of only three atoms: one oxygen and two hydrogen molecules), yet its behavior is rich and complex. For example, it plays a greater and more diverse role in living and non-living processes than other more-complex molecules.

Sometimes referred to as the “universal solvent,”4 water can also dissolve more substances and in greater quantity than any other solvent. In this first article (in a series of 7), we will explore the connection between water’s versatile solvation ability and its finely designed molecular structure.

Chemists have long been aware of the astonishing quantity and diversity of compounds that water could dissolve. In 1913, Harvard biochemist Laurence Henderson published the first quantitative look at the biological relevance of water’s exceptional properties.5Henderson presented an analysis of the main components of both blood serum and urine.6 Even that limited survey led him to conclude that,

It cannot be doubted that if the vehicle of the blood were other than water, the dissolved substances would be greatly restricted in variety and quantity, nor that such restriction must needs be [sic] accompanied by a corresponding restriction of the life processes.7

Modern chemists have since expanded our knowledge of water’s solvent capacity, which has served to reinforce Henderson’s conclusion.

Henderson highlights another reason water’s solvent ability is indispensable for life: the global transport and distribution of salts and minerals.8 To begin with, water plays a major role in breaking down rocks.9 This erosion releases salts and vital elements into the environment. (Erosion is also the first step in creating soil.) Water then acts to mobilize these substances by dissolving them and carrying them down slopes into streams, lakes, rivers, and oceans, all of which may deposit these substances as sediments at various places. Henderson reports that in a given year, the world’s rivers collectively transport approximately 6,500 cubic miles of material—corresponding to five billion tons of dissolved mineral matter, as well as prodigious amounts of sediment.10 All of these minerals are ultimately delivered to lakes, rivers, and oceans, where they are available to both aquatic and terrestrial life. This cycle has been ongoing throughout Earth’s history.

The biological impact of this activity should not be overlooked. All life depends primarily on four elements (carbon, nitrogen, oxygen, and hydrogen), yet also requires small amounts of a variety of other elements. Iron, for example, is essential in certain key proteins, such as hemoglobin (which transports oxygen in blood). Some of these micronutrients, such as molybdenum and arsenic, are referred to as “vital poisons” because we must have them in trace amounts, yet in larger quantities they can be quite toxic.11

Water’s role in dissolving and transporting elements ensures that these extra necessities are available in sufficient quantity for plants and animals. For example, Henderson lists 32 elements available in ordinary salt water.12 Other solvents can’t make such a wide range of elements available.

The Structure of Water

How do we account for water’s extraordinary potential as a solvent? Chemists have answered that question by examining water at a molecular level. Water’s solvation ability can be understood in terms of four key properties, described below.

Bond Angle

The water molecule’s bent shape, with a 104.5° angle between its three atoms (see figure 1a), is one of its most noticeable features. At first glance, one might expect water to be linear so that the two hydrogens can be as far apart as possible. However, the oxygen atom’s four electrons—arranged in two lone pairs and uninvolved in bonding—also repel the hydrogens, thus forcing them to move closer together and form an approximate tetrahedral arrangement (see figure 1b). An ideal tetrahedral arrangement has angles of 109.5° (as seen with methane, CH4), but water’s angle is just a bit smaller (due to the presence of the electron pairs). The valence shell electron pair repulsion (VSEPR) theory provides a more-detailed explanation of water’s bent shape.

Figure 1: The structure of water showing (a) the angle between the three atoms and (b) showing the two electron lone pairs.
Image credit: John Millam


Another important aspect of water’s structure is the polarity of the covalent bondsbetween the central oxygen and its two hydrogens. In molecular bonds there is a tug-of-war between the atoms for possession of the bonding electrons, with the more electronegative element having the greatest pull. Oxygen’s higher electronegativity13means that the electrons spend more time on this atom than on the hydrogen atoms. As a result, the oxygen has a partial-negative charge and the hydrogens have partial-positive charges (see figure 2). This charge separation is known as bond polarity.

Figure 2: The charge distribution or dipole moment in a water molecule (where δ+ denotes partial-positive charges and δ- a partial-negative charge).
Image credit: John Millam

Dipole Moment

If water were linear, the polarity of the molecule’s two bonds would cancel each other out, leaving the molecule nonpolar. And if this were the case, our story would end here—because water would be a poor solvent and wouldn’t be very useful. Instead, its bent shape gives water a partial-positive charge on one (hydrogen) side of the molecule and a partial-negative charge on the other (oxygen) side (see figure 2). This natural separation of charge is known as a permanent dipole moment. Water has the second largest dipole moment of all small molecules (exceeded only by hydrogen fluoride).14

Water’s large dipole moment plays a central role in its ability to act as an effective solvent. For ionic compounds (e.g., salts), water’s negative (oxygen) side interacts strongly with positive ions, and the positive (hydrogen) side with the negative ions, thus pulling them into solution (see figure 3a). In a similar way, water can strongly interact with the partial charges on other polar molecules to dissolve them (see figure 3b

In contrast, water cannot readily dissolve nonpolar molecules because it cannot strongly interact with them. Oils (hydrocarbons) are the classic example. This phenomenon of oil clumping together rather than dissolving in water is referred to as the hydrophobic effect and led to the expression “oil and water don’t mix.”

Water’s inability to dissolve these oily compounds may seem like a defect, but we see this characteristic as part of water’s design for life because it is necessary for the development of cell walls.16 Lipids (fat molecules containing long hydrocarbon side-chains) self-assemble naturally into cell walls due to the hydrophobic effect. Cell walls are crucial to the proper functioning of every living thing. They separate the cell from most everything that surrounds it, yet selectively allow certain nutrients and minerals inside the cell wall, or discharge waste products through carefully controlled channels.

Dielectric Constant

A further consequence of water’s large dipole moment and its molecular shape is its exceptionally high dielectric constant. (With just two exceptions, water’s dielectric constant is higher than that of all other liquids.16) The dielectric constant refers to a solvent’s ability to surround ionic (charged) species.

To illustrate this, consider the case of ordinary table salt (NaCl) and its oppositely charged component ions (Na+ and Cl). In solvents with a low dielectric constant, the electrostatic attraction between the ions would make it difficult to separate them and prevent the salt from dissolving. In water, however, both Na+ and Cl are completely surrounded by a layer of water molecules, weakening the electrostatic attraction between the ions. Water’s tendency to surround other substances makes it energetically favorable for separating salts and other ionic species into distinct ions, thus resulting in their dissolution (see figure 3a).

To help understand this significance, consider amino acids (the building blocks of proteins). They are polar molecules and so should dissolve in water, but their large size greatly reduces their solubility. This obstacle could limit their presence in biological systems; however, their capacity for self-ionization greatly increases their solubility. In self-ionization, one side of the molecule loses a hydrogen ion (H+) and the other side gains one (see figure 4). The net result is two charge centers (one positive and one negative) that the water can latch onto easily and then pull the amino acids into solution. This self-ionization is energetically favorable only in solvents with a high dielectric constant, like water. Without this high dielectric constant, proteins and other large biomolecules would be only marginally soluble, making life in any form impossible.

Figure 4: Self-ionization of the amino acid alanine. 
The natural (unionized) form is on the left and the ionized on the right. The dashed line illustrates the transfer of the hydrogen from the oxygen to the nitrogen.
Image credit: John Millam

Critical Importance of Water’s Bent Shape

It is well understood that water molecules are bent. Nevertheless, it is good to acknowledge that this angle is vital to water’s design. If water were to lose its bend (i.e., straighten out so that the three atoms formed a line), then the polarity of its two bonds would balance (cancel) each other out. This would render water nonpolar even though its bonds are polarized. Consequently, water would have no dipole moment, a small dielectric constant, and it would be a poor solvent. Water’s other properties would be affected as well, but we will explore each of those in subsequent parts of this series.

Today, we have explored four aspects of water’s molecular structure. Individually, these features might seem unremarkable—but collectively they produce an extraordinary molecule. From them we can understand why water is the solvent par excellence and absolutely indispensable for life. In subsequent articles, we will explore more of water’s amazing design features and discuss why they are so critical for life here on Earth.

To access additional parts, please click on a link below:
Part 1  |  Part 2  | Part 3  |  Part 4  |  Part 5  |  Part 6  |  Part 7

Dr. John Millam

Dr. John Millam received his PhD in theoretical chemistry from Rice University in 1997, and currently serves as a programmer for Semichem in Kansas City.

Ken Klos

Mr. Ken Klos received his MS in environmental studies from the University of Florida in 1971, and worked as an environmental/civil engineer for the state of Florida.

Iain D. Sommerville

  1. J. C. Bailer Jr. et al., Chemistry, 2nd ed., (Orlando, FL: Academic Press, 1984), 422.
  2. Water plays such a vital role in supporting life chemistry that scientists have generally held that life is probably impossible without it. Yet some challenge this notion, suggesting that life might arise on a planet or even a moon using a liquid other than water. The possibility of life radically different from what we know is beyond the scope of this series, but we hope to explore it in future articles.
  3. Peter D. Ward and Donald Brownlee, Rare Earth (New York: Copernicus, 2000), 200–201. For an extended discussion of plate tectonics and its importance in sustaining life on this planet, see p. 191–20.
  4. The term “universal solvent” is a misnomer because no solvent can dissolve everything. Originally the term referred to the “alkahest,” a mythical substance sought by medieval alchemists that could dissolve anything—even gold. Nevertheless, water remains the most capable solvent known.
  5. Lawrence Joseph Henderson, The Fitness of the Environment (New York: MacMillan, 1913).
  6. Ibid., 116–17. Specifically, Henderson lists the 10 main components of cow blood serum by concentration. For urine, he lists 37 varieties of organic species and 10 inorganic salts. He also recognized that both contained significantly more substances at lower concentrations.
  7. Ibid., 116.
  8. Ibid., 111–15.
  9. Water aids in erosion in at least four distinct ways. First, the mechanical action of running water—in the form of rain runoff, streams, rivers, and ocean waves—slowly grinds rocks into smaller pieces. Second, water can absorb carbon dioxide (CO2) from the air to form carbonic acid (H2CO3), a weak acid that helps decompose certain rocks. Third, when water freezes it expands. This expansion can crack the hardest rock. Fourth, as glaciers (solid ice) move, they crush rock and carve valleys.
  10. Ibid., 113–14.
  11. Hugh Ross, The Creator and the Cosmos, 3rd ed. (Colorado Springs: NavPress, 2001), 185–86. Vital poisons include chromium, molybdenum, selenium, vanadium, arsenic, boron, chlorine, cobalt, copper, fluorine, iodine, manganese, nickel, phosphorus, potassium, sulfur, tin, and zinc.
  12. Henderson, The Fitness of the Environment, 114.
  13. Fluorine is the most electronegative element, followed by oxygen.
  14. John D. Barrow and Frank J. Tipler, The Anthropic Cosmological Principle (New York: Oxford University Press, 1986), 338.
  15. Michael J. Denton, Nature’s Destiny (New York: The Free Press, 1998), 32.
  16. Barrow and Tipler, The Anthropic Cosmological Principle, 538. Of all liquids, only hydrogen cyanide (HCN) and formaldehyde (H2CO) have a higher dielectric constant than water. However, both are poisonous to most life-forms.